How Low Dose Naltrexone helps with Chronic Pain

LDN low dose naltrexone

A third of Americans suffer from chronic pain, many of whom cannot find relief despite various treatments and medications. Conditions like fibromyalgia, headaches, back pain, and arthritis are just a few of the chronic pain conditions debilitating many Americans. Life with chronic pain can be difficult. It can make getting up in the morning challenging, both physically and emotionally. It can cause depression and increase the risk of suicide. It can cause a person to lose sleep, miss work, and social events. It can even cause relationship challenges and additional health challenges if a person is unable to prepare food, keep up with chores, and becomes bedridden.  Fortunately, some good news has given those suffering from chronic pain hope. Low dose naltrexone can help with chronic pain, like that caused by Fibromyalgia, and provide those suffering with some relief.


Fibromyalgia is one of the most common chronic pain conditions. It is characterized by widespread musculoskeletal pain as well as brain fog and fatigue. This condition is difficult to diagnose, and many who suffer from it find it challenging to get a diagnosis and find effective treatment options. It is a complicated illness, and the inability to diagnose with a blood test makes treatment a challenge. Many treatments currently being prescribed try to reduce the pain and can have a number of side effects. The problem with these treatments is that the benefits, e.g., pain reduction, is only temporary. Users will often become resistant to the drug and can experience side effects with prolonged use. These types of medication don’t treat the underlying issue with is over-sensitive pain receptors and inflammation. There is an alternative to these types of drugs.  Low dose naltrexone, also known as LDN, has proven to be effective in quietening specific pain receptors’ activity, which counteracts the hypersensitivity caused by Fibromyalgia. LDN also lowers the glial cell’s release of inflammatory signals and, as a result, reduces inflammation for the central nervous system.


Clinical evidence of low dose naltrexone for the treatment of fibromyalgia

The effectiveness of LDN to help treat fibromyalgia has been clinically proven and demonstrated in multiple clinical studies.  Stanford conducted a double-blind, placebo-controlled study, which showed that LDN was very effective in improving the symptoms of fibromyalgia. In this study, LDN had reduced the participant’s chronic pain and increased their general life satisfaction. Another study showed similar results and found that LDN had reduced fibromyalgia symptoms in the entire cohort. The reduction in fibromyalgia symptoms was 30% greater in those taking LDN versus those who were taking a placebo.  The researchers in this study stated that “low dose naltrexone may be an effective, highly tolerable, and inexpensive treatment for fibromyalgia.”


Doctor reviews of low does naltrexone use to treat fibromyalgia

Doctors have echoed the same remarks as researchers when discussing the positive effects LDN has on treating fibromyalgia. Dr. Ginevra Liptan, one of the few clinical specialists in the world to focus solely on fibromyalgia and director of The Frida Center for Fibromyalgia in Portland, Oregon, has said that low dose naltrexone is an effective treatment option for chronic pain. They have said that research has shown that inflammation around the nerves in the central nervous system is the key factor in the transition from acute pain to chronic pain. Dr. Liptan went on to say that it is very hard to reduce this type of inflammation, so finding something that does it well and is safe and inexpensive like low dose naltrexone is huge news for those suffering from chronic pain.




Fibromyalgia patient reviews of low dose naltrexone

Robyn started experiencing fibromyalgia symptoms over twenty years ago. She experienced severe chronic pain, fatigue, stomach issues, and severe depression.  It was assumed that the physical pain and depression were a psychiatric condition, and she received electric shock therapy at an in-patient facility.  She was also put on a long list of pharmaceutical drugs that caused terrible side effects while providing no relief to her pain. There was so little research and understanding of the illness, so it wasn’t until 15 years after her symptoms appeared that she received a diagnosis for fibromyalgia.  A pharmacist introduced Robyn to LDN, and she requested a prescription from her doctor.When she first started taking it, she experienced some side-effects, including an increase in her stomach issues. She changed her pharmacy, found a qualified LDN doctor, and immediately started seeing significant improvement, and her pain was greatly reduced, and stomach issues were resolved.


How do patients get low dose naltrexone?

Those looking to buy low dose naltrexone to treat their chronic pain can talk to their doctors.  A telehealth subscription service like AgelessRx, for example, can provide guidance, and if deemed a suitable option for you, one of their doctors can write a prescription and even fulfill it. You can have low dose naltrexone shipped right to your door.  There is also an option to complete an intake form online. The intake form is then reviewed by the medical team, and if approved, you will receive a shipment of LDN.


A third of American’s continue to suffer from chronic pain. There are so many people who, like Robyn, have suffered from the symptoms of fibromyalgia for decades and never received the relief they were hoping for.  Instead, they have seen doctor after doctor and been prescribed harsh medications like opioids that worsened their condition.  Robyn believes all these prescriptions caused her stomach conditions, and it wasn’t until her recent experience with LDN did she finally find relief.  LDN is effective because it works to treat the underlying cause and has little if any, side effects.  If you or someone you know suffers from chronic pain, you should look into low dose naltrexone to determine if it is right for you.